Now, your second edition to better orthopedics

Ingrid Kohlstadt, MD and Ken Cintron, MD (editors)

Unprecedented synthesis of evidence

Authored by 30+ key opinion leaders

Article: Advances in Regenerative Orthopedics

Authored by Christopher H. Evans, PhD, DSc, Advances in Regenerative Orthopedics is an article that appears in Mayo Clin Proc. November 2013;88(11):1323-1339. Dr. Evans is Professor of Orthopedics and Professor of Physical Medicine and Rehabilitation at Mayo. This publication is a very well-written explanation of regenerative orthopedics concepts. Below is the link…

Orthopedic surgeons prescribing fewer opioids

By Allison Pohle  | June 28, 2017 | courtesy of Insigth.Aetna.com Posted by: Regenerative Orthopedics. As doctors consider their role in the nation's opioid epidemic, much attention has been paid to primary care physicians, who account for fully half of the prescription opioids dispensed. But orthopedic surgeons — who rank third, behind internists,…

Regenerative Orthopedics Supplemental Therapy: Dehydrated Human Amnion/Chorion Membrane (dHACM) Allografts as a Therapy for Orthopedic Tissue Repair

The amniotic membrane is a placental tissue that supports the development of the fetus during pregnancy. It is composed of extracellular matrix components such as collagen, fibronectin, and laminin, and contains many different growth factors and cytokines. Amniotic membrane can be PURION(R) Processed to produce dehydrated human amnion/chorion membrane (dHACM,…

Regenerative orthopedics and bone grafting: In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs

from Science Translational Medicine  17 May 2017: Vol. 9, Issue 390 More than 2 million bone-grafting procedures are performed each year using autografts or allografts. However, both options carry disadvantages, and there remains a clear medical need for the development of new therapies for massive bone loss and fracture nonunions. We hypothesized…

Regenerative Orthopedics News: Stem Cells Grown on Plants

Courtesy of Othopedics This Week • Biloine W. Young • Thu, April 6th, 2017 • William L. “Bill” Murphy, M.S., Ph.D., a professor of biomedical engineering at the University of Wisconsin, Madison, creates tiny scaffolds made of plastic or rubber on which he grows human stem cells. To grow clusters of human…

Regenerating Rotator Cuffs with Stem Cells

Apr 04, 2017 | Original story from University of Connecticut - Every time you throw a ball, swing a golf club, reach for a jar on a shelf, or cradle a baby, you can thank your rotator cuff. This nest of tendons connecting your arm bone to your shoulder socket is…

Medscape News: Knee Surgery Does Not Improve Life Quality for Many Patients

by Pam Harrison courtesy of Medscape Medical News, March 29, 2017. Total knee replacement provides minimal quality-of-life benefit for patients with less severe disability at baseline, according to new research. Thus, the treatment, as currently practiced in the United States, is not cost-effective. "Improvements in quality of life with total knee replacement were…

Regenerative Orthopedics News Update

UI team developing bioactive gel to treat knee injuries: Injectable gel encourages self-healing of cartilage. Confocal image shows migration of chondrogenic progenitor cells into the cartilage injury site in response to the stromal cell-derived factor 1(SDF1) contained in the hydrogel. Image courtesy of Yin Yu. Knee injuries are the bane…

Acidic Environment and Wound Healing: A Review

Basavraj S. Nagoba, PhD; Namdev M. Suryawanshi, MD; Bharat Wadher, PhD; Sohan Selkar, MPhT Courtesy of Wounds. 2015;27(1):5-11. Click here for full text on Medscape Abstract and Introduction Abstract Introduction Topical application of acids, such as citric acid, acetic acid, ascorbic acid, boric acid, and algenic acid, to wounds to control infection and…

Regenerative orthopedics: Treatments to enhance orthopedic surgical outcome.

PM R. 2015 Apr;7(4 Suppl):S41-52. doi: 10.1016/j.pmrj.2015.01.015. Murrell WD1, Anz AW2, Badsha H3, Bennett WF4, Boykin RE5, Caplan AI6. Author information Courtesy of Academy of Physical Medicine and Rehabilitation Full Text Open Access: http://www.pmrjournal.org/article/S1934-1482(15)00047-7/pdf Abstract In orthopedic surgery there has been a never-ending quest to improve surgical outcome and the patient's…

FEED MOLECULE TO STEM CELLS, GET BONE REGENERATION

Wed, September 14th, 2016 Researchers from the University of California San Diego have found that if they feed adenosine (ATP), a molecule that occurs naturally in the body, to human pluripotent stem cells, they will regenerate bone tissue. Shyni Varghese, Ph.D. a bioengineering professor at UC San Diego was senior…

3D PRINTED STEM CELLS GROW BONE

Biloine W. Young - South Korean researchers from UNIST ((Ulsan National Institute of Science and Technology) have developed a technique for repairing bone using 3D printed stem cells. A paper, written by 11 of the UNIST researchers and published in the January issue of ACS Nana Journal, explains that 3D printing…