Now, your second edition to better orthopedics.

Ingrid Kohlstadt, MD and Ken Cintron, MD (editors)

An unprecedented synthesis of evidence.

30 chapters by key opinion leaders.

Regenerative Orthopedics News Update

UI team developing bioactive gel to treat knee injuries: Injectable gel encourages self-healing of cartilage. Confocal image shows migration of chondrogenic progenitor cells into the cartilage injury site in response to the stromal cell-derived factor 1(SDF1) contained in the hydrogel. Image courtesy of Yin Yu. Knee injuries are the bane…

Acidic Environment and Wound Healing: A Review

Basavraj S. Nagoba, PhD; Namdev M. Suryawanshi, MD; Bharat Wadher, PhD; Sohan Selkar, MPhT Courtesy of Wounds. 2015;27(1):5-11. Click here for full text on Medscape Abstract and Introduction Abstract Introduction Topical application of acids, such as citric acid, acetic acid, ascorbic acid, boric acid, and algenic acid, to wounds to control infection and…

Regenerative treatments to enhance orthopedic surgical outcome.

PM R. 2015 Apr;7(4 Suppl):S41-52. doi: 10.1016/j.pmrj.2015.01.015. Murrell WD1, Anz AW2, Badsha H3, Bennett WF4, Boykin RE5, Caplan AI6. Author information Courtesy of Academy of Physical Medicine and Rehabilitation Full Text Open Access: http://www.pmrjournal.org/article/S1934-1482(15)00047-7/pdf Abstract In orthopedic surgery there has been a never-ending quest to improve surgical outcome and the patient's…

FEED MOLECULE TO STEM CELLS, GET BONE REGENERATION

Wed, September 14th, 2016 Researchers from the University of California San Diego have found that if they feed adenosine (ATP), a molecule that occurs naturally in the body, to human pluripotent stem cells, they will regenerate bone tissue. Shyni Varghese, Ph.D. a bioengineering professor at UC San Diego was senior…

3D PRINTED STEM CELLS GROW BONE

Biloine W. Young - South Korean researchers from UNIST ((Ulsan National Institute of Science and Technology) have developed a technique for repairing bone using 3D printed stem cells. A paper, written by 11 of the UNIST researchers and published in the January issue of ACS Nana Journal, explains that 3D printing…

BONE MARROW PROTEINS REGULATE BONE-BUILDING CELLS

February 20th, 2017 Elizabeth Hofheinz, M.P.H., M.Ed. Courtesy of Orthopedics This Week. Researchers at the University of Wisconsin (UW)-Madison have just published new work on bone regeneration. The research, published online February 2, 2017 in Stem Cell Reports, contains information on two proteins found in bone marrow that are key…

Cartilage repair in the degenerative ageing knee

Abstract Background and purpose - Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis. A loss of cartilage function and quality is also seen with increasing age. There is a…

A pilot study investigating dietetic weight loss interventions and 12 month functional outcomes of patients undergoing total joint replacement.

Abstract We conducted a pilot randomised controlled trial comparing the effects of a dietetic intervention to usual care, in 40 individuals with a body mass index >30kg/m(2) undergoing total joint replacement (TJR). The dietetic weight loss intervention comprised at least four sessions with an Accredited Practising Dietitian. At 12 months,…

Biological Therapies in Regenerative Sports Medicine.

Abstract Regenerative medicine seeks to harness the potential of cell biology for tissue replacement therapies, which will restore lost tissue functionality. Controlling and enhancing tissue healing is not just a matter of cells, but also of molecules and mechanical forces. We first describe the main biological technologies to boost musculoskeletal…